Therapeutic Targets and Mechanisms for Treatment
Alzheimer's disease is a progressive neurodegenerative disease that is characterized histopathologically by the presence of plaques, mainly composed of Abeta amyloid and the tangles, mainly composed of hyperphosphorylated tau. To date, there is no treatment that can reverse the disease, and all the current therapeutics is directed to cope with the symptoms of the disease. Here we describe the efforts dedicated to attack the plaques and, in more detail, the process of neurofibrillary degeneration, linked to the presence of the hyperphosphorylated microtubule associated protein tau. We have identified the different putative targets for therapeutics and the current knowledge on them.
Treatment for Alzheimer's disease is entering a new and exciting phase, with several new drugs beginning clinical trials. Many of these new therapies are based on our best current understanding of the pathogenesis of Alzheimer's disease, and are designed to try to either slow or halt the progression of the disease. There are several different theories underlying the current efforts, and these are briefly reviewed. Therapies directed against some aspect of beta-amyloid formation, against neurofibrillary tangle formation and against the inflammatory response are all considered, as are the problems associated with each area. It is as yet unclear which, if any, of these approaches will be successful, but the high level of activity in each of these three fields provides some hope that an effective treatment for Alzheimer's disease is on the horizon.
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Therapeutic Targets and Mechanisms for Treatment Conference Speakers
Recommended Sessions
- Alzheimer’s disease
- Alzheimer’s disease and Type 2 Diabetes
- Alzheimer’s disease Diagnosis and Symptoms
- Alzheimer’s disease Imaging
- Alzheimer’s disease Pathophysiology and Disease Mechanisms
- Amyloid Protein in Alzheimer’s and Dementia
- Animal Models and Translational Medicine
- Care Practice and Awareness
- Causes and Prevention of Alzheimer’s
- Current Research in Therapeutic Targets
- Front temporal Dementia
- Geriatrics and Cognitive Disorder
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- Managing Dementia
- Neurodegenerative Diseases
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- Schizophrenia/Psychosis - EURONEURO 2021 (France)
- Seizure Disorders - EURONEURO 2021 (France)
- Self-harm and Suicide Prevention - Annual Mental Health 2021 (Spain)
- Self-harm and Suicide Prevention - Psychosomatic Medicine-2021 (Spain)
- Self-Harm and Suicide Prevention - Stress and Mindfulness 2021 (Spain)
- Self-harm and Suicide Prevention - Psychology Health 2021 (Hungary)
- Self-harm and Suicide Prevention - Psychiatry Meet 2021 (France)
- Semantic Disease - Alzheimer 2021 (USA)
- Sexual Psychiatric Disorder - Psychosomatic Medicine-2021 (Spain)
- Sleep Disorder and Medicine - Psychiatry Mental health 2021 (Belgium)
- Sleep Disorders - Psychiatry Congress 2021 (France)
- Social Psychology - Clinical Psychology 2021 (Austria)
- Social Psychology and Covid-19 - Psychiatry Conference 2021 (Germany)
- Social Science and Humanities - Psychology Health 2021 (Hungary)
- Sociology - Forensic 2021 (Czech Republic)
- Speech-language Pathology and Techniques - Autism 2021 (France)
- sports psychology - Psychiatric congress-2021 (Spain)
- Stress - Psychiatric Congress 2021 (France)
- Stress Management - Mental Health Congress 2021 (Germany)
- Stress, Anxiety and Depression - Psychiatry Mental health 2021 (Belgium)
- Stress, Anxiety and Depression - Annual Mental Health 2021 (Spain)
- Stress, Anxiety and Depression - Psychology 2021 (UK)
- Stress, Anxiety and Depression - Psychosomatic Medicine-2021 (Spain)
- Stress, Anxiety and Depression - Psychiatry Meet 2021 (France)
- Stress, Depression and Anxiety - Psychology Health 2021 (Hungary)
- Stress, Depression and Anxiety: - Psychologists Psychiatrists 2021 (Canada)
- Stress, Depression and Anxiety: - Psychotherapy Conference 2021 (Canada)
- Stress, Depression, Anxiety and Mindfulness - Autism 2021 (France)
- Stress, Types, Causes and Management - Stress and Mindfulness 2021 (Spain)
- Substance Use and Mental Health - Psychiatric congress-2021 (Spain)
- Suicidal Risk - Mental Health Congress 2021 (Germany)
- Suicide and Self harm - Psychologists Psychiatrists 2021 (Canada)
- Suicide and Self harm - Psychotherapy Conference 2021 (Canada)
- Suicide Prevention - Depression Congress 2021 (Switzerland)
- Suicide Prevention - Depression Congress 2021 (Switzerland)
- Suicide Prevention (Disponible en español) - Psychiatric congress-2021 (Spain)
- Suicidology and Suicide Prevention - Psychiatric Congress 2021 (France)
- Technology and the Future of Mental Health Treatment - Psychiatric congress-2021 (Spain)
- Telepsychiatry - Psychiatry Congress 2021 (France)
- The Psychological and Social Impact of Covid-19 - Psychologists Meet 2021 (Netherlands)
- The role of psychiatrists during Covid-19 - Psychiatry Conference 2021 (Germany)
- Therapeutic Targets and Mechanisms for Treatment - Alzheimer’s disease 2021 (Czech Republic)
- Vaccination and Nursing Care - Autism 2021 (France)
- Vascular Dementia - Alzheimer 2021 (USA)
- Vascular Dementia - Alzheimer’s disease 2021 (Czech Republic)
- Vestibular Disorders - EURONEURO 2021 (France)
- Wellness and Health Care - Annual Mental Health 2021 (Spain)
- Women Mental Health and Illness - Psychiatry Meet 2021 (France)
- Women Mental Health and Illness In times of Covid-19 - Psychiatry Conference 2021 (Germany)
- Women’s Health and Midwifery - Annual Mental Health 2021 (Spain)
- Women’s Mental Health and Midwifery - Psychiatry Congress 2021 (France)
- Women’s Psychology - Psychology 2021 (UK)
- Womens Mental Health - Psychiatry Congress 2021 (Germany)
- Yoga & Meditation - Psychosomatic Medicine-2021 (Spain)
- Yoga and Meditation - Stress and Mindfulness 2021 (Spain)
- Yoga, Meditation and Mindfulness - Clinical Psychology 2021 (Austria)
- Yoga, Meditation and Mindfulness - Psychology Health 2021 (Hungary)
