Therapeutic Targets and Mechanisms for Treatment
Alzheimer's disease is a progressive neurodegenerative disease that is characterized histopathologically by the presence of plaques, mainly composed of Abeta amyloid and the tangles, mainly composed of hyperphosphorylated tau. To date, there is no treatment that can reverse the disease, and all the current therapeutics is directed to cope with the symptoms of the disease. Here we describe the efforts dedicated to attack the plaques and, in more detail, the process of neurofibrillary degeneration, linked to the presence of the hyperphosphorylated microtubule associated protein tau. We have identified the different putative targets for therapeutics and the current knowledge on them.
Treatment for Alzheimer's disease is entering a new and exciting phase, with several new drugs beginning clinical trials. Many of these new therapies are based on our best current understanding of the pathogenesis of Alzheimer's disease, and are designed to try to either slow or halt the progression of the disease. There are several different theories underlying the current efforts, and these are briefly reviewed. Therapies directed against some aspect of beta-amyloid formation, against neurofibrillary tangle formation and against the inflammatory response are all considered, as are the problems associated with each area. It is as yet unclear which, if any, of these approaches will be successful, but the high level of activity in each of these three fields provides some hope that an effective treatment for Alzheimer's disease is on the horizon.
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Therapeutic Targets and Mechanisms for Treatment Conference Speakers
Recommended Sessions
- Alzheimer’s disease
- Alzheimer’s disease and Type 2 Diabetes
- Alzheimer’s disease Diagnosis and Symptoms
- Alzheimer’s disease Imaging
- Alzheimer’s disease Pathophysiology and Disease Mechanisms
- Amyloid Protein in Alzheimer’s and Dementia
- Animal Models and Translational Medicine
- Care Practice and Awareness
- Causes and Prevention of Alzheimer’s
- Current Research in Therapeutic Targets
- Front temporal Dementia
- Geriatrics and Cognitive Disorder
- Insulin Resistance on the development of Alzheimer’s disease
- Managing Dementia
- Neurodegenerative Diseases
- Therapeutic Targets and Mechanisms for Treatment
- Vascular Dementia
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- Psychoanalysis and Psychosis - Mental Health Summit 2021 (Czech Republic)
- Psychoanalysis, Psychosis and Psychometrics - PSYCHOLOGY EDUCATION 2022 (Hungary)
- Psychological and Psychosocial Interventions - PSYCHOLOGY EDUCATION 2022 (Hungary)
- Psychological Disorder - Clinical Psychology 2021 (Austria)
- Psychological disorders - Psychologists Meet 2021 (Netherlands)
- Psychological Evaluation & Assessment - Psychiatric Congress 2022 (Aland Islands)
- Psychological problems associated with COVID-19 - Psychologists Meet 2021 (Netherlands)
- Psychologists Meetings - Psychology 2021 (UK)
- Psychology - Mental Health Summit 2021 (Czech Republic)
- Psychology - Psychiatric 2021 (USA)
- Psychology - Psychosomatic Medicine 2022 (UK)
- Psychology - Psychology 2021 (UK)
- Psychology - Psychologists Meet 2021 (Netherlands)
- Psychology & Psychiatry - Psychology 2021 (UK)
- Psychology & Psychiatry - Mental Health 2022 (Germany)
- Psychology and Human Resilience - PSYCHOLOGY EDUCATION 2022 (Hungary)
- Psychology and Human Resilience - Annual Mental Health 2022 (France)
- Psychology and Psychological Disorders - Psychology Health 2021 (Hungary)
- Psychology and Psychological Resilience - Stress and Mindfulness 2021 (Spain)
- Psychology and Psychotherapy - Mental Health Congress-2021 (Singapore)
- Psychology Awareness - Psychology 2021 (UK)
- Psychology, Autism and Youth Protection - Positive Psychology 2022 (France)
- Psychometrics, Psychosis and Psychological Assessment: - Stress and Mindfulness 2021 (Spain)
- PSYCHOPATHOLOGY & PSYCHOTHERAPY - Psychiatry Congress 2022 (Czech Republic)
- Psychopathology and Antidepressants - Stress and Mindfulness 2021 (Spain)
- Psychopathology and Antidepressants - Stress and Mindfulness 2021 (Spain)
- Psychopathology and Psychoanalysis - Psychology Health 2021 (Hungary)
- Psychopathology and Psychopathy - Euro Psychiatry 2022 (Italy)
- Psychopathology and Psychopathy - Psychiatry Congress 2021 (France)
- Psychopathology and Psychotherapy - Psychology 2021 (UK)
- Psychopharmacology - World Psychiatry 2021 ()
- Psychopharmacology - WORLD PSYCHIATRIC CONGRESS-2021 (Spain)
- Psychopharmacology - Euro Psychiatry 2022 (Italy)
- Psychopharmacology - Psychosomatic Medicine 2022 (UK)
- Psychopharmacology - Psychology 2021 (UK)
- Psychopharmacology - Psychiatric 2021 (USA)
- Psychopharmacology - Addiction 2021 (Netherlands)
- Psychopharmacology and Neuropharmacology - Annual Mental Health 2022 (France)
- Psychopharmacology Role: Mental Health - Mental Health 2022 (Germany)
- Psychopharmacology Role: Psychology - Psychology 2021 (UK)
- Psychosis - Psychiatric Congress 2022 (Aland Islands)
- PSYCHOSIS - Psychiatry Congress 2022 (Czech Republic)
- Psychosis and Psychometrics - Psychology Health 2021 (Hungary)
- Psychosis, Medication and Early Intervention - Psychiatry Mentalhealth 2022 (Singapore)
- Psychosis: - Neuro Experts 2021 (Canada)
- Psychosis: - Psychotherapy Conference 2021 (Canada)
- Psychosis: - Psychologists Psychiatrists 2021 (Canada)
- Psychosocial Rehabilitation - Psychiatric Congress 2022 (Aland Islands)
- Psychosomatic Disorders - Mental Health 2022 (Germany)
- Psychosomatic Disorders - Mental Health Congress 2022 (Japan)
- Psychosomatic Disorders - Psychology 2021 (UK)
- Psychosomatic Disorders - Psychosomatic Medicine 2022 (UK)
- Psychosomatic Disorders - Psychiatric 2021 (USA)
- Psychosomatic Disorders & Psychosomatic Medicine - Psychiatry Congress 2021 (France)
- Psychosomatic medicine - World Psychiatry 2021 ()
- Psychosomatic Medicine - Psychosomatic Medicine 2022 (UK)
- Psychosomatic medicine - WORLD PSYCHIATRIC CONGRESS-2021 (Spain)
- Psychosomatic Medicine - Psychiatric 2021 (USA)
- Psychosomatic Medicine and Sleep Medicine - Euro Neuro 2021 (France)
- Psychotherapies - WORLD PSYCHIATRIC CONGRESS-2021 (Spain)
- Psychotherapy - Psychosomatic Medicine 2022 (UK)
- Psychotherapy - Psychology 2021 (UK)
- Psychotherapy - Psychiatric 2021 (USA)
- Psychotherapy - Psychiatry Conference 2022 (France)
- Psychotherapy - Mental Health Summit 2021 (Czech Republic)
- Psychotherapy and Counceling - Stress and Mindfulness 2021 (Spain)
- Psychotherapy and Counselling Psychology - Positive Psychology 2022 (France)
- Psychotherapy and its Advances - Psychiatric Congress 2022 (Aland Islands)
- Psychotherapy and Psychopharmacology - Psychology Health 2021 (Hungary)
- Psychotherapy/Analysis - Euro Neuro 2021 (France)
- Public Health and Patient Safety - Annual Mental Health 2022 (France)
- Regenerative medicine - Mental Health Summit 2021 (Czech Republic)
- Rehabilitation and Family Therapies - Addiction 2021 (Netherlands)
- Rehabilitation and Recovery - Clinical Psychology 2021 (Austria)
- Research, Education and Case studies on Mental Health - Psychiatry Mentalhealth 2022 (Singapore)
- Resistant depressive disorder - Depression Congress 2021 (France)
- Role of Tele-Psychiatry during Lockdown - Psychiatric 2021 (USA)
- Schizophrenia - Psychiatric Congress 2022 (Aland Islands)
- SCHIZOPHRENIA - Psychiatry Congress 2022 (Czech Republic)
- Schizophrenia - World Psychiatry 2021 ()
- Schizophrenia - Mental Health Congress 2022 (Japan)
- Schizophrenia - WORLD PSYCHIATRIC CONGRESS-2021 (Spain)
- Schizophrenia - Mental Health Summit 2021 (Czech Republic)
- Schizophrenia and Bipolar Disorders - Annual Mental Health 2022 (France)
- Schizophrenia and Bipolar Disorders - Psychology Health 2021 (Hungary)
- Schizophrenia and Bipolar Disorders - PSYCHOLOGY EDUCATION 2022 (Hungary)
- Schizophrenia and Bipolar Disorders - Stress and Mindfulness 2021 (Spain)
- Schizophrenia and Bipolar Disorders - Stress and Mindfulness 2021 (Spain)
- Schizophrenia and Bipolar Disorders - Mental Health Congress 2022 (Japan)
- Schizophrenia and Nursing Care - Psychiatry Mentalhealth 2022 (Singapore)
- Schizophrenia and Obsessive Compulsive Disorder (OCD) - Mental Health Congress-2021 (Singapore)
- Schizophrenia/Psychosis - Euro Neuro 2021 (France)
- Science of Psychology and Applied Research - PSYCHOLOGY EDUCATION 2022 (Hungary)
- Seizure Disorders - Euro Neuro 2021 (France)
- Self-harm and Suicide Prevention - Psychology Health 2021 (Hungary)
- Self-harm and Suicide Prevention - Mental Health Congress 2022 (Japan)
- Self-Harm and Suicide Prevention - Stress and Mindfulness 2021 (Spain)
- Self-harm and Suicide Prevention - PSYCHOLOGY EDUCATION 2022 (Hungary)
- Sexual Orientation and LGBT - Positive Psychology 2022 (France)
- Sleep Disorder - Mental Health Congress 2022 (Japan)
- Sleep Disorder and Medicine - Psychiatry Mentalhealth 2022 (Singapore)
- Sleep Disorders - Psychiatry Conference 2022 (France)
- Sleep Disorders - Psychiatry Congress 2021 (France)
- Sleep Disorders - Psychiatric 2021 (USA)
- Sleep Disorders - Psychosomatic Medicine 2022 (UK)
- Social Psychology - Clinical Psychology 2021 (Austria)
- Social Psychology - Psychiatry Conference 2022 (France)
- Social Psychology - Euro Psychiatry 2022 (Italy)
- Social Science and Humanities - Psychology Health 2021 (Hungary)
- Sports psychology - WORLD PSYCHIATRIC CONGRESS-2021 (Spain)
- Sports psychology - World Psychiatry 2021 ()
- Stress - Psychiatric Congress 2022 (Aland Islands)
- Stress and Anxiety - Mental Health Congress 2022 (Japan)
- Stress and Pain Management - Mental Health Summit 2021 (Czech Republic)
- Stress, Anxiety and Depression - Psychology 2021 (UK)
- Stress, Anxiety and Depression - Psychiatry Mentalhealth 2022 (Singapore)
- Stress, Anxiety and Depression - Annual Mental Health 2022 (France)
- Stress, Anxiety and Depression - Mental Health 2022 (Germany)
- Stress, Anxiety and Depression - Positive Psychology 2022 (France)
- Stress, Depression and Anxiety - PSYCHOLOGY EDUCATION 2022 (Hungary)
- Stress, Depression and Anxiety - Psychology Health 2021 (Hungary)
- Stress, Depression and Anxiety: - Psychologists Psychiatrists 2021 (Canada)
- Stress, Depression and Anxiety: - Psychotherapy Conference 2021 (Canada)
- Stress, Types, Causes and Management - Stress and Mindfulness 2021 (Spain)
- Suicide and Self harm - Psychologists Psychiatrists 2021 (Canada)
- Suicide and Self harm - Psychotherapy Conference 2021 (Canada)
- Suicide and Self harm - Mental Health Summit 2021 (Czech Republic)
- Suicide Prevention - Depression Congress 2021 (France)
- Suicide Prevention - Depression Congress 2021 (France)
- Suicide Prevention (Disponible en español) - World Psychiatry 2021 ()
- Suicide Prevention (Disponible en español) - WORLD PSYCHIATRIC CONGRESS-2021 (Spain)
- Suicidology and Suicide Prevention - Psychiatric Congress 2022 (Aland Islands)
- Technology and the Future of Mental Health Treatment - World Psychiatry 2021 ()
- Technology and the Future of Mental Health Treatment - WORLD PSYCHIATRIC CONGRESS-2021 (Spain)
- Telepsychiatry - Psychiatry Congress 2021 (France)
- Telepsychiatry - Psychosomatic Medicine 2022 (UK)
- The Psychological and Social Impact of Covid-19 - Psychologists Meet 2021 (Netherlands)
- Theory, Religion and Language - Positive Psychology 2022 (France)
- Track 10: Emergency Psychiatry - Psychiatry Summit 2022 (Czech Republic)
- Track 11: Stress and pain management - Psychiatry Summit 2022 (Czech Republic)
- Track 12: Palliative and Hospice - Psychiatry Summit 2022 (Czech Republic)
- Track 13: Neuroscience and Neuropsychiatry - Psychiatry Summit 2022 (Czech Republic)
- Track 14: Sports, Social and Military Psychiatry - Psychiatry Summit 2022 (Czech Republic)
- Track 15: Psychosomatic Medicine - Psychiatry Summit 2022 (Czech Republic)
- Track 16: Experimental Psychology - Psychiatry Summit 2022 (Czech Republic)
- Track 17: Yoga and Meditation - Psychiatry Summit 2022 (Czech Republic)
- Track 18: Forensic Psychiatry - Psychiatry Summit 2022 (Czech Republic)
- Track 19: Alzheimer’s and Dementia - Psychiatry Summit 2022 (Czech Republic)
- Track 1: Psychiatry and Psychology - Psychiatry Summit 2022 (Czech Republic)
- Track 20: Research, Education and Case Studies on Mental Health - Psychiatry Summit 2022 (Czech Republic)
- Track 2: Child and Adolescent Psychiatry - Psychiatry Summit 2022 (Czech Republic)
- Track 3: Mental Health and Psychiatric Nursing - Psychiatry Summit 2022 (Czech Republic)
- Track 4: Addiction Psychiatry - Psychiatry Summit 2022 (Czech Republic)
- Track 5: Telepsychiatry - Psychiatry Summit 2022 (Czech Republic)
- Track 6: Anxiety and Depression Disorders - Psychiatry Summit 2022 (Czech Republic)
- Track 7: Midwifery & Women’s Health - Psychiatry Summit 2022 (Czech Republic)
- Track 8: Cross Cultural Psychology - Psychiatry Summit 2022 (Czech Republic)
- Track 9: Human Cognition - Psychiatry Summit 2022 (Czech Republic)
- TRAUMA - Psychiatry Congress 2022 (Czech Republic)
- Trauma Stress-Related Disorders - Psychiatry Conference 2022 (France)
- Vestibular Disorders - Euro Neuro 2021 (France)
- Women and Mental Health - Mental Health Congress 2022 (Japan)
- Women and Mental Health - Psychiatric 2021 (USA)
- Women and Mental Health - Psychosomatic Medicine 2022 (UK)
- Women’s Health and Midwifery - Annual Mental Health 2022 (France)
- Women’s Mental Health - Mental Health 2022 (Germany)
- Women’s Mental Health and Disorders - Euro Psychiatry 2022 (Italy)
- Women’s Mental Health and Midwifery - Psychiatry Congress 2021 (France)
- Women’s Psychology - Psychology 2021 (UK)
- Yoga and Meditation - Mental Health Summit 2021 (Czech Republic)
- Yoga and Meditation - Stress and Mindfulness 2021 (Spain)
- Yoga, Meditation and Mindfulness - Psychology Health 2021 (Hungary)
- Yoga, Meditation and Mindfulness - Clinical Psychology 2021 (Austria)
- Yoga, Meditation and Spirituality - Positive Psychology 2022 (France)