Therapeutic Targets and Mechanisms for Treatment
Alzheimer's disease is a progressive neurodegenerative disease that is characterized histopathologically by the presence of plaques, mainly composed of Abeta amyloid and the tangles, mainly composed of hyperphosphorylated tau. To date, there is no treatment that can reverse the disease, and all the current therapeutics is directed to cope with the symptoms of the disease. Here we describe the efforts dedicated to attack the plaques and, in more detail, the process of neurofibrillary degeneration, linked to the presence of the hyperphosphorylated microtubule associated protein tau. We have identified the different putative targets for therapeutics and the current knowledge on them.
Treatment for Alzheimer's disease is entering a new and exciting phase, with several new drugs beginning clinical trials. Many of these new therapies are based on our best current understanding of the pathogenesis of Alzheimer's disease, and are designed to try to either slow or halt the progression of the disease. There are several different theories underlying the current efforts, and these are briefly reviewed. Therapies directed against some aspect of beta-amyloid formation, against neurofibrillary tangle formation and against the inflammatory response are all considered, as are the problems associated with each area. It is as yet unclear which, if any, of these approaches will be successful, but the high level of activity in each of these three fields provides some hope that an effective treatment for Alzheimer's disease is on the horizon.
Related Conference of Therapeutic Targets and Mechanisms for Treatment
February 10-11, 2021
4th International Conference on Clinical Psychology and Psychopathology
Vienna, Austria
February 10-11, 2021
2nd International Summit on Mental Disorders and Illness
Amsterdam, Netherlands
February 12-13, 2021
2nd European Psychologists, Psychiatrists and Mental Health Experts Meeting
Amsterdam, Netherlands
February 12-13, 2021
30th International Conference on Psychology Health, Human Resilience, and Well-being
Vienna, Austria
February 15-16, 2021
8th International Conference on Depression, Anxiety and Stress Management
London, UK
February 22-23, 2021
32nd International Conference on Adolescent Medicine and Child Psychology
London, UK
March 15-16, 2021
32nd World Summit on Positive Psychology, Happiness, Mindfulness, and Wellness
Paris, France
March 17-18, 2021
6th International Conference on Clinical and Counseling Psychology
Singapore, Singapore
May 03-04, 2021
9th International Conference on Mental Health and Human Resilience
Edinburgh, Scotland
June 28-29, 2021
15th International Conference on Alzheimers Disease and Dementia
Prague, Czech Republic
July 05-06, 2021
38th International Conference on Psychiatry & Psychosomatic Medicine
Valencia, Spain
November 24-25, 2021
31th International Conference on Psychology, Psychotherapy and Mental Wellness
London, UK
Therapeutic Targets and Mechanisms for Treatment Conference Speakers
Recommended Sessions
- Alzheimer’s disease
- Alzheimer’s disease and Type 2 Diabetes
- Alzheimer’s disease Diagnosis and Symptoms
- Alzheimer’s disease Imaging
- Alzheimer’s disease Pathophysiology and Disease Mechanisms
- Amyloid Protein in Alzheimer’s and Dementia
- Animal Models and Translational Medicine
- Care Practice and Awareness
- Causes and Prevention of Alzheimer’s
- Current Research in Therapeutic Targets
- Front temporal Dementia
- Geriatrics and Cognitive Disorder
- Insulin Resistance on the development of Alzheimer’s disease
- Managing Dementia
- Neurodegenerative Diseases
- Therapeutic Targets and Mechanisms for Treatment
- Vascular Dementia
Related Journals
Are you interested in
- Addiction - Mental Health Congress 2021 (Germany)
- Addiction - Mental Health Congress 2021 (UK)
- Addiction and Mental Health - Mental Health 2021 (Italy)
- Addiction and Psychology - Psychology 2021 (UK)
- Addiction Medicine and Therapy - Psychiatry 2021 (Canada)
- Addiction Psychiatry - Psychiatry 2021 (Germany)
- Addiction, Addictive Disorders and Recovery - Annual Mental Health 2021 (Netherlands)
- Addiction, Alcoholism, Drug Abuse and Recovery - Positive Psychology 2021 (France)
- Addiction, Alcoholism, Drug Abuse and Recovery - Psychology Health 2021 (Austria)
- Adolescent Psychology - Psychology 2021 (UK)
- Adolescent Psychology - Child Psychology 2021 (UK)
- Adult and Geriatric Psychiatry - Psychology 2021 (UK)
- Adult and Geriatric Psychiatry - Mental Health 2021 (Italy)
- Advanced Therapeutics for Mental Health Disorders - Psychiatry Meet 2021 (UK)
- Alzheimer’s and Dementia - Psychiatry Meet 2021 (UK)
- Alzheimer’s and Dementia - Psychology Health 2021 (Austria)
- Alzheimer’s disease - Alzheimer’s disease 2021 (Czech Republic)
- Alzheimer’s Disease - Euro Mental Disorder 2021 (Netherlands)
- Alzheimer’s disease and Type 2 Diabetes - Alzheimer’s disease 2021 (Czech Republic)
- Alzheimer’s disease Diagnosis and Symptoms - Alzheimer’s disease 2021 (Czech Republic)
- Alzheimer’s disease Imaging - Alzheimer’s disease 2021 (Czech Republic)
- Alzheimer’s disease Pathophysiology and Disease Mechanisms - Alzheimer’s disease 2021 (Czech Republic)
- Amyloid Protein in Alzheimer’s and Dementia - Alzheimer’s disease 2021 (Czech Republic)
- Animal Models and Translational Medicine - Alzheimer’s disease 2021 (Czech Republic)
- Anxiety - Mental Health Congress 2021 (Germany)
- Anxiety Disorder - Euro Mental Disorder 2021 (Netherlands)
- Applied and Health Psychology - Psychology Health 2021 (Austria)
- Asperger’s Syndrome and Social Communication - Autism 2021 (France)
- Attention Deficit Hyperactivity Disorder (ADHD) - Annual Mental Health 2021 (Netherlands)
- Autism Awareness and Child Safety - Autism 2021 (France)
- Autism spectrum disorder - Child Psychology 2021 (UK)
- Autism spectrum disorder - Psychology 2021 (UK)
- Autism Spectrum Disorders (ASD) - Annual Mental Health 2021 (Netherlands)
- Autism Spectrum Disorders and Research - Autism 2021 (France)
- Autism: Causes, Risk Factors and Diagnosis - Autism 2021 (France)
- Behavioral Health Disorders - Mental Health Congress 2021 (UK)
- Behavioral Health Treatment and Services - Mental Health Congress 2021 (UK)
- Bipolar Disorder and Schizophrenia - Psychiatry Meet 2021 (UK)
- Bipolar disorders - Mental Health Congress 2021 (UK)
- Birth Defects, Disease Control and Prevention - Autism 2021 (France)
- Buddhism, Wisdom and Self-transcendence - Positive Psychology 2021 (France)
- Care Practice and Awareness - Alzheimer’s disease 2021 (Czech Republic)
- Case Reports and Management of Mental Health - Annual Mental Health 2021 (Netherlands)
- Causes and Prevention of Alzheimer’s - Alzheimer’s disease 2021 (Czech Republic)
- Child Abuse - Mental Health 2021 (Italy)
- Child Abuse - Psychiatry 2021 (Canada)
- Child Abuse - Psychiatry 2021 (Germany)
- Child Abuse - Psychology 2021 (UK)
- Child and Adolescent Counselling Psychology - Psychology 2021 (UK)
- Child and Adolescent Counselling Psychology - Child Psychology 2021 (UK)
- Child and Adolescent Psychiatry - Annual Mental Health 2021 (Netherlands)
- Child and Adolescent Psychiatry - Psychology 2021 (UK)
- Child and Adolescent Psychiatry - Psychiatry Meet 2021 (UK)
- Child and Adolescent Psychiatry - Mental Health 2021 (Italy)
- Child and Adolescent Psychiatry - Psychiatry 2021 (Canada)
- Child Health and Psychology - Mental Health 2021 (Italy)
- Child Health and Psychology - Psychology 2021 (UK)
- Child Health and Psychology - Child Psychology 2021 (UK)
- Child Nutrition and Parenting - Autism 2021 (France)
- Child Psychiatry - Mental Health Congress 2021 (Germany)
- Child Psychiatry and Behavioral Sciences - Autism 2021 (France)
- Child Psychology and Developmental Disabilities - Autism 2021 (France)
- Child Psychology and Developmental Medicine - Psychology Health 2021 (Austria)
- Child Psychology, Autism and Protection - Positive Psychology 2021 (France)
- Chronic Mental Illness - Euro Mental Disorder 2021 (Netherlands)
- Clinical & Counseling Psychology - Mental Health Congress 2021 (UK)
- Clinical Child Psychology - Child Psychology 2021 (UK)
- Clinical Psychology - Mental Health 2021 (Italy)
- Clinical Psychology - Psychology 2021 (UK)
- Clinical Psychology - Psychiatry 2021 (Germany)
- Clinical Psychology, Research and Practice - Psychology Health 2021 (Austria)
- Cognition: Attention, Learning and Memory - Autism 2021 (France)
- Cognitive and Behavioral Psychology - Psychology 2021 (UK)
- Cognitive Neuroscience - Psychology 2021 (UK)
- Cognitive Neuroscience - Child Psychology 2021 (UK)
- Current Research in Therapeutic Targets - Alzheimer’s disease 2021 (Czech Republic)
- Dementia - Euro Mental Disorder 2021 (Netherlands)
- Dementia and Alzheimers Disease - Annual Mental Health 2021 (Netherlands)
- Depression - Euro Mental Disorder 2021 (Netherlands)
- Depression - Mental Health Congress 2021 (Germany)
- Depression - Mental Health Congress 2021 (UK)
- Developmental Discipline and Behaviour Management - Child Psychology 2021 (UK)
- Diagnostic Approaches towards Psychiatry - Psychiatry Meet 2021 (UK)
- Down Syndrome and Genetic Disorders - Autism 2021 (France)
- Eating Disorders - Euro Mental Disorder 2021 (Netherlands)
- Eating Disorders and Obesity - Annual Mental Health 2021 (Netherlands)
- Educational and Behavioral Interventions - Autism 2021 (France)
- Educational Psychology - Child Psychology 2021 (UK)
- Educational Psychology - Psychology 2021 (UK)
- Entrepreneurs Investment Meet - Psychology 2021 (UK)
- Entrepreneurs Investment Meet - Child Psychology 2021 (UK)
- Entrepreneurship and Organisation Development - Positive Psychology 2021 (France)
- Epilepsy - Euro Mental Disorder 2021 (Netherlands)
- Forensic Psychology - Child Psychology 2021 (UK)
- Forensic Psychology - Psychology 2021 (UK)
- Forensic Psychology and Criminology - Psychology Health 2021 (Austria)
- Front temporal Dementia - Alzheimer’s disease 2021 (Czech Republic)
- Geriatric Psychiatry - Psychiatry 2021 (Germany)
- Geriatrics and Cognitive Disorder - Alzheimer’s disease 2021 (Czech Republic)
- Happiness and Quality of Life - Autism 2021 (France)
- Happiness, Eudaimonia and Wellness - Positive Psychology 2021 (France)
- Health, Wellness and Lifestyle - Psychology Health 2021 (Austria)
- Healthcare and Digital Health - Positive Psychology 2021 (France)
- Herbal Medicine for Mental Health - Psychiatry Meet 2021 (UK)
- Human Resilience - Psychology 2021 (UK)
- Human Resilience - Psychiatry 2021 (Germany)
- Human Resilience - Psychiatry 2021 (Canada)
- Human Resilience - Mental Health 2021 (Italy)
- Humanities and Social Sciences - Positive Psychology 2021 (France)
- Impact of Covid 19 on Mental Health - Psychiatry Meet 2021 (UK)
- Industrial and Organizational Psychology - Positive Psychology 2021 (France)
- Industrial and Organizational Psychology - Psychology Health 2021 (Austria)
- Insulin Resistance on the development of Alzheimer’s disease - Alzheimer’s disease 2021 (Czech Republic)
- Interventions: School-Age, Adolescent and Adult - Autism 2021 (France)
- Leadership and Motivation - Positive Psychology 2021 (France)
- LGBT and Sexual Orientation - Positive Psychology 2021 (France)
- Management and Treatment of Psychological Syndrome - Psychiatry Meet 2021 (UK)
- Managing Dementia - Alzheimer’s disease 2021 (Czech Republic)
- Maternal Factors and Epidemiological Studies - Autism 2021 (France)
- Medical Education and Cancer Therapy - Medical Education 2021 (UK)
- Medical Education and Clinical Evaluation - Medical Education 2021 (UK)
- Medical Education and Drugs - Medical Education 2021 (UK)
- Medical Education and e-Learning - Medical Education 2021 (UK)
- Medical Education and Epidemiology - Medical Education 2021 (UK)
- Medical Education and Health Education - Medical Education 2021 (UK)
- Medical Education and Nanotechnology - Medical Education 2021 (UK)
- Medical Education and Public Health - Medical Education 2021 (UK)
- Medical Education and Research - Medical Education 2021 (UK)
- Mental and Behavioral Health Strengthening - Mental Health Congress 2021 (UK)
- Mental Disorders - Psychiatry 2021 (Germany)
- Mental Disorders and Rehabilitation - Mental Health Congress 2021 (UK)
- Mental Health - Mental Health 2021 (Italy)
- Mental Health - Mental Health Congress 2021 (UK)
- Mental Health - Mental Health Congress 2021 (Germany)
- Mental Health - Psychiatry 2021 (Germany)
- Mental Health & Rehabilitation - Psychiatry 2021 (Canada)
- Mental Health and Human Resilience - Psychology Health 2021 (Austria)
- Mental Health and Nursing - Psychiatry 2021 (Canada)
- Mental Health and Quality of Life - Positive Psychology 2021 (France)
- Mental Health and Rehabilitation - Psychiatry Meet 2021 (UK)
- Mental Health and Well-being - Autism 2021 (France)
- Mental Health and Well-being - Annual Mental Health 2021 (Netherlands)
- Mental Health Awareness - Mental Health 2021 (Italy)
- Mental Health Awarness - Psychiatry 2021 (Canada)
- Mental health Nursing - Mental Health Congress 2021 (UK)
- Mental Illness - Euro Mental Disorder 2021 (Netherlands)
- Mental Illness and Health Care - Psychiatry 2021 (Canada)
- Mindfulness and Compassion - Positive Psychology 2021 (France)
- Mindfulness Yoga & Medication - Mental Health 2021 (Italy)
- Mindfulness Yoga & Medication - Psychology 2021 (UK)
- Mindfulness Yoga and Medication - Annual Mental Health 2021 (Netherlands)
- Neonatal Psychology - Child Psychology 2021 (UK)
- Neonatal Psychology - Psychology 2021 (UK)
- Neurodegenerative Diseases - Alzheimer’s disease 2021 (Czech Republic)
- Neuroimaging and Radiology - Euro Mental Disorder 2021 (Netherlands)
- Neurological and Developmental Disorders - Autism 2021 (France)
- Neurological Disorders - Euro Mental Disorder 2021 (Netherlands)
- Neurology - Euro Mental Disorder 2021 (Netherlands)
- Neurology and Neurological Disorders - Annual Mental Health 2021 (Netherlands)
- Neurology and Neuropsychology - Psychology Health 2021 (Austria)
- Neuroscience - Psychiatry 2021 (Canada)
- Neuroscience and Neuropsychiatry - Annual Mental Health 2021 (Netherlands)
- Neuroscience and Neuropsychiatry - Psychiatry Meet 2021 (UK)
- Neurosurgery - Psychiatry 2021 (Canada)
- Nursing Education and Global Health - Medical Education 2021 (UK)
- Nursing Education, Practice and Medicare - Annual Mental Health 2021 (Netherlands)
- Occupational Therapy and Rehabilitation Counseling - Autism 2021 (France)
- Pediatric Neurology - Euro Mental Disorder 2021 (Netherlands)
- Pediatric psychiatry - Psychiatry 2021 (Germany)
- Pediatrics - Psychology 2021 (UK)
- Pediatrics - Child Psychology 2021 (UK)
- Pediatrics, Neonatology and Healthcare - Autism 2021 (France)
- Philosophy, Religion and Language - Positive Psychology 2021 (France)
- Positive Education, Learning and Coaching - Positive Psychology 2021 (France)
- Positive Neuroscience and Cognition - Positive Psychology 2021 (France)
- Positive Psychology - Psychology 2021 (UK)
- Positive Psychology - Child Psychology 2021 (UK)
- Positive Psychology and Happiness - Psychology Health 2021 (Austria)
- Positive Psychology and Mental Awareness - Annual Mental Health 2021 (Netherlands)
- Positive Psychology and PERMA Model - Positive Psychology 2021 (France)
- Positive Psychology Interventions and Optimism - Positive Psychology 2021 (France)
- Post-traumatic stress disorder (PTSD) and Mental Illness - Psychology Health 2021 (Austria)
- Post-Traumatic Stress Disorder and Phobias - Annual Mental Health 2021 (Netherlands)
- Power of Yoga & Medication - Psychiatry 2021 (Canada)
- Psychiatric and Mental Health Nursing - Child Psychology 2021 (UK)
- Psychiatric and Mental Health Nursing - Annual Mental Health 2021 (Netherlands)
- Psychiatric and Psychology Nursing - Psychology 2021 (UK)
- Psychiatric Disorders or Psychological Syndromes - Psychology 2021 (UK)
- Psychiatric Nursing - Mental Health 2021 (Italy)
- Psychiatric Nursing - Psychology 2021 (UK)
- Psychiatric Nursing and Nursing Education - Positive Psychology 2021 (France)
- Psychiatric Rehabilitation - Mental Health 2021 (Italy)
- Psychiatric Rehabilitation - Psychology 2021 (UK)
- Psychiatric, Psychology & Mental Health Nursing - Psychology Health 2021 (Austria)
- Psychiatry - Psychiatry 2021 (Canada)
- Psychiatry - Mental Health Congress 2021 (Germany)
- Psychiatry - Mental Health Congress 2021 (UK)
- Psychiatry - Psychology 2021 (UK)
- Psychiatry and Mental Health - Psychiatry Meet 2021 (UK)
- Psychiatry and Psychiatric Disorders - Positive Psychology 2021 (France)
- Psychiatry and Psychiatric Disorders - Annual Mental Health 2021 (Netherlands)
- Psychiatry and Psychological Disorders - Mental Health 2021 (Italy)
- Psychiatry and Psychology Practices - Mental Health 2021 (Italy)
- Psychological Disorders - Child Psychology 2021 (UK)
- Psychologists Meetings - Child Psychology 2021 (UK)
- Psychologists Meetings - Psychology 2021 (UK)
- Psychology - Psychology 2021 (UK)
- Psychology & Psychiatry - Psychiatry 2021 (Germany)
- Psychology & Psychiatry - Psychology 2021 (UK)
- Psychology & Psychiatry - Mental Health 2021 (Italy)
- Psychology and Clinical Psychology - Psychiatry 2021 (Canada)
- Psychology and Human Resilience - Annual Mental Health 2021 (Netherlands)
- Psychology and Psychological Disorders - Psychology Health 2021 (Austria)
- Psychology and Resilience - Positive Psychology 2021 (France)
- Psychology Awareness - Psychology 2021 (UK)
- Psychopathology - Psychiatry Meet 2021 (UK)
- Psychopathology and Psychoanalysis - Psychology Health 2021 (Austria)
- Psychopathology and Psychotherapy - Psychology 2021 (UK)
- Psychopathology and Psychotherapy - Child Psychology 2021 (UK)
- Psychopharmacology - Child Psychology 2021 (UK)
- Psychopharmacology - Psychology 2021 (UK)
- Psychopharmacology and Neuropharmacology - Annual Mental Health 2021 (Netherlands)
- Psychopharmacology Role: Mental Health - Mental Health 2021 (Italy)
- Psychopharmacology Role: Psychology - Psychology 2021 (UK)
- Psychosis and Psychometrics - Psychology Health 2021 (Austria)
- Psychosis-Medication, Counselling and Early Intervention - Psychiatry Meet 2021 (UK)
- Psychosomatic Disorders - Mental Health 2021 (Italy)
- Psychosomatic Disorders - Psychology 2021 (UK)
- Psychosomatic Medicine - Psychiatry 2021 (Canada)
- Psychotherapy - Psychology 2021 (UK)
- Psychotherapy and Counseling Psychology - Positive Psychology 2021 (France)
- Psychotherapy and Psychopharmacology - Psychology Health 2021 (Austria)
- Public Health and Patient Safety - Annual Mental Health 2021 (Netherlands)
- Research, Education and Case studies on Mental health - Psychiatry Meet 2021 (UK)
- Rett Syndrome and Women’s Health - Autism 2021 (France)
- Safety, Family Support and Financial Planning - Autism 2021 (France)
- Schizophrenia - Mental Health Congress 2021 (UK)
- Schizophrenia - Psychiatry 2021 (Canada)
- Schizophrenia - Euro Mental Disorder 2021 (Netherlands)
- Schizophrenia and Bipolar Disorders - Psychology Health 2021 (Austria)
- Schizophrenia and Bipolar Disorders - Annual Mental Health 2021 (Netherlands)
- Self-harm and Suicide Prevention - Psychology Health 2021 (Austria)
- Self-harm and Suicide Prevention - Psychiatry Meet 2021 (UK)
- Self-harm and Suicide Prevention - Annual Mental Health 2021 (Netherlands)
- Social Science and Humanities - Psychology Health 2021 (Austria)
- Speech Language Pathology - Psychiatry 2021 (Canada)
- Speech-language Pathology and Techniques - Autism 2021 (France)
- Spine Disorders - Euro Mental Disorder 2021 (Netherlands)
- Stress and Anxiety - Mental Health Congress 2021 (UK)
- Stress Management - Mental Health Congress 2021 (Germany)
- Stress, Anxiety and Depression - Annual Mental Health 2021 (Netherlands)
- Stress, Anxiety and Depression - Mental Health 2021 (Italy)
- Stress, Anxiety and Depression - Psychology 2021 (UK)
- Stress, Anxiety and Depression - Positive Psychology 2021 (France)
- Stress, Anxiety and Depression - Psychiatry Meet 2021 (UK)
- Stress, Anxiety and Depression - Psychiatry 2021 (Canada)
- Stress, Depression and Anxiety - Psychology Health 2021 (Austria)
- Stress, Depression, Anxiety and Mindfulness - Autism 2021 (France)
- Stroke - Euro Mental Disorder 2021 (Netherlands)
- Suicidal Risk - Mental Health Congress 2021 (Germany)
- Suicide Prevention and Self-harm Reduction - Positive Psychology 2021 (France)
- Therapeutic Targets and Mechanisms for Treatment - Alzheimer’s disease 2021 (Czech Republic)
- Types of Mental Health’s - Euro Mental Disorder 2021 (Netherlands)
- Vaccination and Nursing Care - Autism 2021 (France)
- Vascular Dementia - Alzheimer’s disease 2021 (Czech Republic)
- Well-being and Flourishing - Positive Psychology 2021 (France)
- Wellness and Health Care - Annual Mental Health 2021 (Netherlands)
- Women Mental Health and Illness - Psychiatry Meet 2021 (UK)
- Women’s Health and Midwifery - Annual Mental Health 2021 (Netherlands)
- Women’s Mental Health - Mental Health 2021 (Italy)
- Women’s Mental Health - Euro Mental Disorder 2021 (Netherlands)
- Women’s Psychology - Psychology 2021 (UK)
- Womens Mental Health - Psychiatry 2021 (Germany)
- Yoga, Meditation and Mindfulness - Psychology Health 2021 (Austria)
- Yoga, Meditation and Spirituality - Positive Psychology 2021 (France)
